. Author manuscript; available in PMC: 2022 Feb 26.

Published in final edited form as: Anticancer Res. 2019 Jun;39(6):2721–2727. doi: 10.21873/anticanres.13398

Table II.

Tumour control probability (TCP) for the simulated treatments.

Central hypoxia	D₅₀ (Gy)
	1 Fraction	3 Fractions	5 Fractions	8 Fractions
No radiation-induced vessel collapse, HF=5%	42.7	47.4	48.0	50.0
Radiation-induced vessel collapse, HF=25%	45.7	51.6	52.2	54.1
Multi-island hypoxia		D₅₀ (Gy)
	1 Fraction	3 Fractions	5 Fractions	8 Fractions
No radiation-induced vessel collapse, HF=5%	42.8	47.5	47.9	49.9
Radiation-induced vessel collapse, HF=15%	44.2	49.4	50.0	52.0

TCP: Tumour control probability; D₅₀: dose required to achieve 50% tumour control probability; HF: hypoxic fraction.