Fig. 3.

Bioimaging of brain by LA-ICP-MS at µm scale. A) Mass spectrum of a line scan (top left) and images of selected metals and non-metals measured by LA-ICP-MS in routine mode. B) Metal distributions in the human brain measured by LA-ICP-MS. C) Comparison of copper images of mice brain sections from 2- to 14-month-old mice measured by LA-ICP-MS.

(a) Image adapted of Becker et al. [125] under permission of Elsevier. (b) Image adapted of Becker [127] under permission of Wiley. (c) Images adapted of Becker et al. [125] under permission of Elsevier.