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. 2022 Feb 25;22:260. doi: 10.1186/s12913-022-07655-6

Table 1.

Markov Model Parameter Estimates and Assumptions

Parameter Value Sensitivity Analysis Range
1. DR transition probabilities
  No to Mild [27] 0.07 0.01–0.10
  Mild to Moderate [27] 0.19 0.166–0.214
  Moderate to VTDR [27] 0.17 0.147–0.193
  VTDR to Stable [28] 0.90 0.881–0.919
  Stable to Blindness [29] 0.02 0.002–0.03
  VTDR to Blindness [29] 0.09 0.07–0.11
2. Utility
  No DR [30] 0.94 0.83–1.05
  Mild DR [30] 0.87 0.73–1.01
  Moderate DR [30] 0.87 0.73–1.01
  VTDR [30] 0.83 0.74–0.92
  Stable DR [31] 0.85 0.72–0.78
  Blindness [30] 0.81 0.73–0.89
3. Disutility of DR [32] 0.066 -
4. Mortality multipliers [26]
  Blindness 2.34 2.22–2.46
  Diabetes 1.90 1.04–2.7
5. Sensitivity, %
  AI Screening screening [23] 90.79 86.40-94.10
  Ophthalmologist screening [24] 96.00 94.79-97.21
6. Specificity, %
  AI screening [23] 98.50 97.80-99.00
  Ophthalmologist screening [24] 94.67 94.57-97.43
7. Compliance of screening [33], % 86.00 -

DR Diabetic retinopathy, VTDR Vision-threatening diabetic retinopathy