Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 26;22:211. doi: 10.1186/s12885-022-09294-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 1 — Expression levels of B7-H3 and B7-H4 PAAD tissues. A Representative microphotographs revealing low B7-H3 expression in para-tumor tissues and low, medium, and high B7-H3 expression in tumor tissues using IHC staining. Brown, B7-H3. Blue, haematoxylin. Bar = 200 μm. B7-H3 was mostly localized to the cytomembrane of tumor cells and tumor stroma. B The semi-quantitative analysis of B7-H3 in tumor and para-tumor tissues. B7-H3 was significantly up-regulated in tumor tissues compared with para-tumor tissues. C Representative microphotographs revealing low B7-H4 expression in para-tumor tissues and low, medium, and high B7-H4 expression in tumor tissues using IHC staining. Brown, B7-H4. Blue, haematoxylin. Bar = 200 μm. B7-H4 was mostly localized to the cytomembrane of tumor cells but not tumor stroma D The semi-quantitative analysis of B7-H4 in tumor and para-tumor tissues. B7-H4 was significantly up-regulated in tumor tissues compared with para-tumor tissues. E Correlation between B7-H3 and B7-H4 expression in the TMA cohort. No obvious correlation was found between B7-H3 and B7-H4 expression. F Correlation between B7-H3 and B7-H4 mRNA expression in the TCGA database. B7-H3 was positively correlated with B7-H4 expression