Table 1.
Demographics and Clinical Characteristics of All Pediatric Patients with Primary Nephrotic Syndrome
| Characteristics | Whole Group (n=171) | CYP3A5 Expresser Group (n=84) | CYP3A5 Nonexpresser Group (n=87) |
|---|---|---|---|
| Male/Female | 128/43 | 64/20 | 64/23 |
| Age (years) | 5.4±3.5 | 5.9±3.5 | 4.9±3.3 |
| Weight (kg) | 19.5±8.3 | 20.8±8.8 | 18.4±7.8 |
| Alanine transaminase (ALT, U/L) | 19.416±14.449 | 17.760±11.063 | 21.039±17.093 |
| Aspartate transaminase (AST, U/L) | 28.180±11.714 | 27.700±11.249 | 28.660±12.257 |
| serum creatinine (SCr, µmol/L) | 30.733±13.678 | 32.855±13.657 | 28.466±13.448 |
| TAC C0/D ((ng/mL)/(mg/kg)) | 84.660 (20.300~228.004) | 61.622 (20.300~139.360) | 95.763 (42.900~228.004) |
Notes: Data are presented as median with P25~P75 (Percentile:25%~75%), mean ± standard deviation or amount.