| Methods |
Prospective RCT |
| Participants |
97 participants; 51 (intervention) 46 (control) |
| Interventions |
RSL (intervention) versus WGL (control); no crossover |
| Outcomes |
Successful localization; excision; margins |
| Notes |
Source of funding not stated; mixed pathology |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Not reported |
| Allocation concealment (selection bias) |
Unclear risk |
Not reported |
| Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
Not blinded, but outcome unlikely to be influenced (acceptable as per surgical design) |
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
Not blinded, but outcome unlikely to be influenced (acceptable as per surgical design) |
| Incomplete outcome data (attrition bias)
All outcomes |
High risk |
Five participants excluded due to missing data |
| Selective reporting (reporting bias) |
Low risk |
Only malignant lesions included in analysis for rate of involved margins |
| Other bias |
High risk |
Mixed Pathology |
