Table 3.

Antifungal drugs used to treat mucormycosis: a summary of recommendations

Antifungal agent	Dose	Duration	Source
Posaconazole	• Posaconazole IV/tablet: 1 × 300 mg from day 2, 2 × 300 mg day 1 • Oral suspension: 2 × 400 mg/day or 4 × 200 mg/day	6 months	(Greenberg et al. 2006; Graves et al. 2016; A. Skiada et al. 2011)
Amphotericin B (ABCL, AMB, LAMB)	CNS participation: 1 mg/100 g per day LAMB No CNS participation: 0.5 mg/100 g per day LAMB	Usually 6–12 weeks	(Shoham et al. 2010; Walsh et al. 2012)
Combination	• Isavuconazole or posaconazole and LAMB • LAMB + echinocandin		(Kyvernitakis et al. 2016; Rodriguez et al. 2018; Vujanovic et al. 2017)
Isavuconazole	IV or PO: 3 × 200 mg day 1, 1 × 200 mg/day from day 3	3 months (oral/iv/both)	(DiPippo et al. 2019; Maertens et al. 2016; Mellinghoff et al. 2018)