Table 1. Features of the studies analyzed for iron deficiency anemia, Sysmex XN Aplpha/10/300/1000, XE 2100/5000 (Sysmex Corporation Kobe, Japan), Technicon H3, (Bayer, Germany), Advia 120, ADVIA 2120i (Siemens AG, Erlangen, Germany).
ACD: Anemia of chronic disease, AI: Inflammation anemia, CHr: Reticulocyte hemoglobin content, CKD: Chronic kidney disease, CRF: Chronic renal failure ESRD: End-stage renal disease, ID: Iron deficiency, IDA: Iron deficiency anemia, MCV:Mean corpuscular volume, NIDA: Non-iron deficiency anemia, TM: β-Talasemia minor, TSAT: Transferrin Saturation
| FIRST AUTHOR | YEAR | COUNTRY | DEVICE | STUDY DESIGN | PATIENT GROUP | PATIENT/ CONTROL | TOTAL NUMBER | FEMALE | MALE | RESEARCHED PARAMETERS |
|---|---|---|---|---|---|---|---|---|---|---|
| Chaipokam et al. (46) | 2017 | Thailand | Sysmex- XE Alpha | Prospective cohort | Adult- Anemia | Control, IDA, Talasemi, Talasemi trait, AI | 267 | 190 | 77 | MCV, CHr |
| Rehu et al. (35) | 2011 | Finland | ADVIA 120 and 2120 | Retrospective | Adult- Anemia | Control, IDA, ACD | 250 | 138 | 112 | CHr, MCV |
| Brugnara et al. (8) | 1999 | Amerika | Technicon H3 | Iron Deficiency Children | Control, IDA, ID | 210 | 90 | 210 | CHr, MCV, Ferritin | |
| Balci et al. (47) | 2016 | Turkey | Sysmex ADVIA 2120i | Case-control | 6–12 Years Old Children | Control, IDA, B12 vitamin deficiency, mixed anemia | 112 | 52 | 60 | CHr, MCV, Ferritin |
| Ceylan et al. (48) | 2007 | Turkey | ADVIA 120 | Case-control | Adult- Anemia | Control, IDA, ID, Talasemi minor, B12 vitamin deficiency | 131 | 91 | 40 | CHr, MCV |
| Cai et al. (49) | 2017 | China | ADVIA 120 | Case-control | Adults | Control, IDA, NIDA | 140 | 100 | 40 | CHr, MCV, Ferritin |
| LUO et al. (50) | 2007 | China | ADVIA 120 | Case-control | Pre- menopausal Women- Anemia | Control, IDA, NIDA | 142 | 142 | CHr, MCV | |
| Dinh et al. (51) | 2020 | Vietnam | Sysmex ADVIA 2120i | Retrospective | Adult-ESRD | Control, IDA, NIDA, ESRD, IDA-ESRD | 312 | 188 | 124 | CHr, MCV |
| Ageeli et al. (52) | 2013 | Saudi Arabia | ADVIA 2120i | Case-control | Adult- Anemia | Control, IDA, ACD, CRF | 320 | 170 | 150 | CHr, MCV, Ferritin, TSAT |
| Buttarello et al. (53) | 2016 | Italy | Sysmex XE-5000 | Case-control | Adult- Anemia | Control, IDA, ID, NIDA, trait b talasemia | 290 | CHr, MCV, Ferritin | ||
| Uçar et al. (33) | 2019 | Turkey | Sysmex XN 1000 | Case-control | Adult- Anemia | Control, IDA, ID, NIDA | 217 | 171 | 46 | CHr, MCV, Ferritin,TSAT |
| Toki et al. (54) | 2017 | Japan | Sysmex XN 300/XE | Case-control | Adult- Anemia | Control, IDA, ID, NIDA | 211 | 148 | 63 | CHr, MCV, Ferritin,TSAT |
| Vázquez-López et al. (55) | 2019 | Spain | ADVIA 120 | Case-control | 1–16 Years Old Children | Contol, IDA, ID | 1239 | 620 | 619 | CHr, MCV, Ferritin,TSAT |
| Malczewska- Lenczowska et al. (56) | 2017 | Poland | ADVIA 120 | Case-control | Sports women | Control, ID stage I, ID stage II | 219 | 219 | CHr, MCV, Ferritin | |
| Chinudomwong et al. (57) | 2020 | Thailand | Sysmex XN-10 | Case-control | Adult- Anemia | Control, IDA, IDA-inflamma- tion, NIDA-AI, NIDA-CKD, Talasemi | 938 | 603 | 335 | CHr, MCV, Ferritin |
| Urrechaga et al. (58) | 2011 | Spain | Sysmex XE 5000 | Case-control | Anemia and Talasemia | Control, talasemia trait, mild IDA, severe IDA | 473 | CHr, MCV, Ferritin, TSAT | ||
| Rungngu et al. (59) | 2016 | Indonesia | Sysmex XE-2100 | Cross-section- al | 6–12 Years Old Children- Anemia | Control, IDA, NIDA | 50 | 17 | 33 | CHr, Ferritin |