Table 2.

Multivariable analysis for prognostic factors on overall survival

Variable	n = 650	HR	95% CI	p value
Lauren classification
Intestinal	200 (31%)	*
Diffuse	194 (30%)	1.99	1.53–2.59	< 0.001
Mixed	37 (6%)	0.95	0.57–1.57	0.826
Unknown	219 (34%)	1.45	1.12–1.71	0.005
WHO PS
0	466 (72%)	*
1	184 (28%)	1.38	1.12–1.71	0.003
BMI
≥ 30	87 (13%)	*
25–30	235 (36%)	0.98	0.70–1.37	0.883
18.5–25	312 (48%)	1.29	0.93–1.77	0.124
≤ 18.5	16 (2%)	1.07	0.55–2.08	0.843
Allocated treatment
Postop CT	395 (50%)	*
Postop CRT	393 (50%)	1.06	0.87–1.30	0.545
CEA	Missing n = 138
≤ 6 µg/L	543 (84%)	*
> 6 µg/L	107 (16%)	1.43	1.11–1.85	0.007
CA 19-9	Missing n = 138
≤ 37 kU/L	499 (77%)	*
> 37 kU/L	151 (23%)	1.79	1.42–2.25	< 0.001