Table 3.

Epigenome-wide significant CpG-sites associated with AUD.

Caudate nucleus
Chr	Position	CG	Gene	Effect	Std Err	P	Direction	FDR
15	78729669	cg04214706	IREB2	−0.393	0.073	7.58E−08	+−	0.03
5	74633012	cg26685658	HMGCR	−5.92	1.105	8.53E−08	−	0.03
Ventral striatum
8	117961971	cg17163967	SLC30A8	0.504	0.0882	1.09E−08	++	0.007
1	178998656	cg23933289	FAM20B	0.269	0.0482	2.36E−08	++	0.008
15	69908472	cg27512762	PCAT29	0.17	0.032	6.80E−08	−+	0.016
7	1008720	cg02028351	COX19	0.18	0.034	1.28E−07	++	0.017
16	68563886	cg02941431		−0.251	0.047	1.27E−07	−	0.017
3	183274235	cg06427508	KLHL6	0.379	0.072	1.44E−07	++	0.017
12	132882652	cg16767842	GALNT9	0.239	0.046	1.74E−07	−+	0.017
16	4901809	cg02741291	UBN1	0.579	0.113	2.61E−07	?+	0.023
16	1946176	cg10824492		−0.147	0.029	3.35E−07	−	0.026
19	35168316	cg18564234	SCGB1B2P; ZNF302	−0.776	0.153	4.13E−07	−	0.029
13	73687406	cg06630619		−0.43	0.085	4.76E−07	−	0.03
11	1215457	cg23618269	MUC5AC	−0.432	0.086	5.25E−07	−	0.03
14	96177134	cg13545750	TCL1A	−0.226	0.046	7.21E−07	−	0.039
5	79331052	cg04360099	THBS4	0.303	0.062	1.03E−06	++	0.048
6	29400397	cg26754552		0.277	0.057	9.88E−06	++	0.048
11	59390857	cg02849689		−0.298	0.061	1.24E−06	−	0.048
18	11147785	cg12049992	PIEZO2	−0.28	0.058	1.20E−06	+−	0.048
17	18210650	cg16021181	TOP3A	−0.307	0.063	1.11E−06	−	0.048

Chr chromosome, Direction: (+) hypermethylated, (−) hypomethylated, (?) CpGs not available in one batch, FDR false discovery rate corrected p-value.