Table 1.
Baseline sociodemographic and clinical characteristics of rheumatic and musculoskeletal disease patients
| Variable | RMD patients admitted with COVID-19 (n = 105) |
|---|---|
| Women, n (%) | 67 (63.81) |
| Age, mean (s.d.), years | 66.82 (14.83) |
| Active smoker | 3 (2.8) |
| Diagnosis, n (%) | |
| ARD, n (%) | 54 (51.4) |
| SAC | 25 (28.8) |
| PMR | 6 (5.71) |
| SLE | 2 (1.90) |
| MCTD | 5 (4.76) |
| SjS | 4 (3.81) |
| Vasculitis | 1 (0.95) |
| SS | 2 (1.90) |
| Polychondritis | 1 (0.95) |
| PM | 1 (0.95) |
| RP | 3 (2.83) |
| CIA | 29 (27.6) |
| RA | 19 (18.10) |
| Axial spondyloarthritis | 6 (5.71) |
| PsA | 3 (2.86) |
| Polyarthritis | 1 (0.95) |
| NARD | 51 (48.6) |
| OA | 9 (8.57) |
| Tendonitis | 17 (16.19) |
| Osteoporosis | 2 (1.90) |
| FM | 1 (0.95) |
| Low back pain | 5 (4.76) |
| Neck pain | 1 (0.95) |
| Knee disorder | 8 (7.62) |
| Carpal tunnel | 1 (0.95) |
| Microcrystalline arthritis | 7 (6.67) |
| Co-morbidities, n (%) | |
| Hypertension | 32 (30.48) |
| Dyslipidaemia | 22 (20.95) |
| Depression | 3 (2.86) |
| Diabetes mellitus | 10 (9.52) |
| Heart diseasea | 13 (12.38) |
| Ischaemic vascular diseaseb | 5 (4.76) |
| Liver disease | 7 (6.67) |
| Kidney disease | 4 (3.81) |
| Lung disease (ILD/COPD) | 15 (14.28) |
| Cancer | 6 (5.71) |
| Venous thrombosis/lung embolism | 2 (1.90) |
| Thyroid disease | 8 (7.62) |
| Laboratory data at baseline admission, median (IQR) | |
| D-dimer, ng/ml | 1147 (451–1395) |
| Lymphocyte count, ×109/l | 976 (600–1290) |
| CRP, mg/dl | 8.85 (2.62–12.95) |
| Creatinine, mg/dl | 0.96 (0.66–1.08) |
| Ferritin, ng/ml | 530 (189–718) |
| COVID-19-related treatments during admission, n (%) | |
| HCQ | 92 (87.62) |
| Glucocorticoids | 59 (56.19) |
| Azithromycin | 35 (33.33) |
| Tocilizumab | 8 (7.62) |
| Darunavir/cobicistat | 5 (4.76) |
| Remdesivir | 1 (0.95) |
| Length of stay, mean (s.d.), days | 15.39 (14.42) |
a
Including: valve disease, arrythmias, cardiomyopathy, heart failure and pericarditis.
b
Including: stroke, cardiovascular and peripheral vascular disease.
ARD: autoimmune inflammatory rheumatic diseases; CIA: chronic inflammatory arthritis; COPD: chronic obstructive pulmonary disease; COVID-19: coronavirus disease 2019; ILD: interstitial lung disease; IQR: interquartile range; NARD: non-autoimmune rheumatic and musculoskeletal disorders; RMD: rheumatic and musculoskeletal disease; SAC: systemic autoimmune conditions.