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. 2021 Apr 11;59(4):1263–1279. doi: 10.1007/s13197-021-05091-8

Table 4.

Major peptide groups and their bioactivities (Meisel 2004)

Bioactive peptide group Protein precursor Bioactivity Systems affected
Casomorphins β- and α-casein Opioid agonists, ACE-inhibitory, immunomodulatory Nervous, cardiovascular immune
α-Lactorphin α-Lactalbumin (α-La) Opioid agonists, ACE-inhibitory Nervous, cardiovascular
β-Lactorphin β-Lactoglobulin (β-Lg) Opioid agonists, ACE-inhibitory, smooth muscle contraction (Ileum) Nervous, cardiovascular, digestive
Lactoferroxins Lactoferrin Opioid antagonists Nervous
Casoxins κ-Casein Opioid antagonists, ACE-inhibitory, some smooth muscle contraction Nervous, cardiovascular, digestive
Casokinins β- and α-casein Antihypertensive, immunomodulatory, cytomodulatory Immune, cardiovascular
Casoplatelins κ-casein, transferrin Antithrombiotic Cardiovascular
Immunopeptides β- and α-casein Immunomodulatory Immune
Phosphopeptides β- and α-casein Mineral carriers Digestive
Lactoferricin Lactoferrin Antimicrobial, immunomodulatory Immune, digestive