Table 1.
Ovarian stimulation protocols in different age brackets and data of in vitro fertilization and embryo transfer.
| Total | 38/39 y | 40/41 y | 42/43 y | ≥44 y | P | |
|---|---|---|---|---|---|---|
| N = 826 | N = 424 | N = 226 | N = 118 | N = 58 | ||
| GnRH antagonist | 37.41% (309/826) | 31.83% (135/424) | 35.84% (81/226) | 47.46% (56/118) | 63.79% (37/58) | <0.001 |
| GnRH-a long | 26.63% (220/826) | 33.49% (142/424) | 20.80% (47/226) | 22.03% (26/118) | 8.62% (5/58) | <0.001 |
| Micro-stimulation | 21.31% (176/826) | 18.16% (77/424) | 25.66% (58/226) | 23.73% (28/118) | 22.41% (13/58) | 1.38 |
| GnRH-a ultra-long | 12.35% (102/826) | 15.09% (64/424) | 14.16% (32/226) | 4.24% (5/118) | 1.72% (1/58) | <0.001 |
| Progestin primed ovarian stimulation | 2.30% (19/826) | 1.42% (6/424) | 3.54% (8/226) | 2.54% (3/118) | 3.44% (2/58) | 0.335 |
| Number of oocytes | 6 (3,10) | 7 (4,10) | 6 (4,10) | 5 (3,8) | 3 (2,5.25) | <0.001 |
| Number of transferable embryos | ||||||
| 1 | 130 | 12.50% (53/424) | 15.93% (36/226) | 22.88% (27/118) | 24.14% (14/58) | 0.012 |
| 2 | 342 | 46.46% (197/424) | 34.51% (78/226) | 36.44% (43/118) | 41.37% (24/58) | 0.018 |
| 3 | 160 | 13.21% (56/424) | 27.43% (62/226) | 23.73% (28/118) | 24.14% (14/58) | <0.001 |
| 4–11 | 194 | 27.83% (118/424) | 22.12% (50/226) | 16.95% (20/118) | 10.34% (6/58) | 0.004 |
| Number of transplant cycles | ||||||
| 1 | 678 | 77.12% (327/424) | 86.28% (195/226) | 87.29% (103/118) | 91.38% (53/58) | 0.002 |
| 2 | 129 | 20.75% (88/424) | 10.62% (24/226) | 10.17% (12/118) | 8.62% (5/58) | 0.001 |
| ≥3 | 19 | 2.12% (9/424) | 3.10% (7/226) | 2.54% (3/118) | 0.0% (0/58) | 0.553 |