TABLE 3.

Mediation analysis of sense of coherence, social support, and coping behaviors in the effect of stigma on HRQoL (N = 221–219).

IV = Stigma	DV
	PWB (Model 1)			SWB (Models 2–9)					EWB (Models 10–14)					FWB (Models 15–22)					BCS (Models 23–26)					FACT-G (Models 27–34)					FACT-B (Models 35–45)
	Single mediation			Single mediation			Parallel mediation (c′ = −0.14*, P = 0.026)		Single mediation			Parallel mediation (c′ = −0.25***)		Single mediation			Parallel mediation (c′ = −0.21**)	Single mediation			Parallel mediation (c′ = −0.31**)		Single mediation			Parallel mediation (c′ = −0.32***)		Single mediation			Parallel mediation (c′ = −0.34***)
Mediators	c′	ab	95%CI	c′	ab	95%CI	ab	95%CI	c′	ab	95%CI	ab	95%CI	c′	ab	95%CI			c′	ab	95%CI	ab	95%CI	c′	ab	95%CI	ab	95%CI	c′	ab	95%CI	ab	95%CI
Comprehensibility									−0.32***	−0.05	HC4 [−0.09, −0.01]	−0.01	[−0.01, 0.00]						−0.33***	−0.05	[−0.10, −0.02]	−0.04	[−0.09, −0.01]						−0.44***	−0.04	[−0.08, −0.01]	−0.02	[−0.05, 0.02]
Manageability																													−0.44***	−0.04	[−0.07, −0.01]	−0.01	[−0.04, 0.02]
Meaningfulness	−0.33***	−0.04	[−0.09, −0.006]	−0.18**	−0.06	[−0.11, −0.02]	−0.04	[−0.08, −0.01]	−0.31***	−0.06	HC4 [−0.12, −0.02]	−0.05	HC4 [−0.10, −0.01]	−0.27***	−0.05	[−0.10, −0.01]	−0.03	[−0.08, 0.01]	−0.34***	−0.04	[−0.08, −0.01]	−0.03	[−0.07, 0.004]	−0.38***	−0.07	[−0.12, −0.03]	−0.06	[−0.10, −0.02]	−0.41***	−0.07	[−0.12, −0.03]	−0.05	[−0.09, −0.01]
Sense of coherence				−0.18**	−0.06	[−0.11, −0.02]			−0.29***	−0.08	HC4 [−0.13, −0.04]			−0.26***	−0.06	[−0.10, −0.02]			−0.31***	−0.07	[−0.13, −0.03]			−0.38***	−0.08	[−0.12, −0.03]			−0.40***	−0.08	[−0.13, −0.04]
Emotional-informational				−0.17**	−0.07	[−0.12, −0.02]								−0.26***	−0.05	[−0.10, −0.02]								−0.41***	−0.05	[−0.09, −0.02]			−0.44***	−0.04	[−0.08, −0.01]
Affectionate				−0.18**	−0.06	[−0.11, −0.01]								−0.27***	−0.05	[−0.09, −0.01]								−0.41***	−0.04	[−0.09, −0.01]			−0.44***	−0.04	[−0.08, −0.01]
Tangible				−0.19**	−0.05	[−0.10, −0.01]																							−0.45	−0.02	[−0.05, −0.001]
Positive social interaction				−0.15**	−0.09	[−0.15, −0.04]								−0.24***	−0.07	[−0.13, −0.03]								−0.38***	−0.07	[−0.12, −0.03]			−0.41***	−0.07	[−0.11, −0.03]
Total social support				−0.17**	−0.07	[−0.12, −0.02]	−0.06	[−0.11, −0.02]						−0.26***	−0.05	[−0.09, −0.02]	−0.03	[−0.07, −0.01]						−0.41***	−0.05	[−0.08, −0.01]	−0.03	[−0.06, −0.003]	−0.44***	−0.04	[−0.08, −0.01]	−0.02	[−0.05, 0.00]
Positive reframing									−0.32***	−0.06	HC4 [−0.10, −0.02]	−0.04	HC4 [−0.08, −0.005]	−0.26***	−0.05	[−0.10, −0.02]	−0.04	[−0.08, −0.003]						−0.40***	−0.06	[−0.10, −0.02]	−0.03	[−0.07, −0.004]	−0.43***	−0.05	[−0.10, −0.02]	−0.03	[−0.07, −0.002]

*P < 0.05, ** P < 0.01, ** P < 0.001.

HRQol, Health-related quality of life; IV, Independent variable; DV, Dependent variable; PWB, Physical wellbeing; SWB, Social wellbeing; EWB, Emotional wellbeing; FWB, Functional wellbeing; BCS, Breast cancer subscale; Arm, Arm subscale; FACT-G, Functional assessment cancer therapy–General; FACT-B, Functional assessment cancer therapy–breast cancer; c′, Direct effect of stigma on DVs; ab (a × b), Indirect effect of stigma on DVs; CI, Confidence interval.

One missing value for positive reframing (N = 220).

Age, education, employment status, social participation frequency, insurance coverage, patient’s history of major psychological problems, chemotherapy status, history of mastectomy surgery, history of radiotherapy status was included as covariates.

All Cis are bolded to denote significant as per Benjamini-Hochberg Procedure reported in Supplementary Material of supporting results in detail.

HC4: Heteroscedasticity consistent standard error of Caribari-Neto is used.

Models numbers denote the figures included in Supplementary Material of model figures.