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. 2022 Feb 15:annrheumdis-2021-221636. doi: 10.1136/annrheumdis-2021-221636

Table 1.

Characteristics of patients with SLE at the time of COVID-19 diagnosis (n=1922)

Characteristics Mean (SD) or number (percentage)
Age, years, mean (SD) 44.4 (14.1)
Female, n (%) 1734 (90.4%)
Race/Ethnicity, n (%)
 White 639 (33.3%)
 Non-white 1102 (57.3%)
 Missing 181 (9.4%)
Region, n (%)
 Europe 543 (28.3%)
 USA and Canada 555 (28.9%)
 Latin America 643 (33.5%)
 Other 181 (9.4%)
Time period, n (%)
 <15 June 2020 733 (38.1%)
 16 June–30 September 2020 444 (23.1%)
 1 October 2020–12 April 2021 745 (38.8%)
Comorbidities, n (%)
 0 1098 (57.1%)
 1 511 (26.6%)
 ≥2 313 (16.3%)
Specific comorbidities, n (%)
 Chronic renal insufficiency or ESRD 223 (11.8%)
 Hypertension or cardiovascular disease 597 (31.1%)
Disease activity, n (%)
 Remission 587 (30.5%)
 Minimal or low 700 (36.4%)
 Moderate 229 (11.9%)
 Severe or high 77 (4.0%)
 Missing 329 (17.1%)
Prednisone dose*, n (%)
 0 mg/day 846 (44.0%)
 1–5 mg/day 467 (24.3%)
 6–9 mg/day 78 (4.1%)
 ≥10 mg/day 280 (14.6%)
 Missing 251 (13.1%)
Medication category, n (%)
 Antimalarials only 665 (34.6%)
 No SLE therapy 230 (12.0%)
 Oral synthetic drug monotherapy with methotrexate, leflunomide or sulfasalazine only† 175 (9.1%)
 Oral synthetic drug monotherapy with (mycophenolate/mycophenolic acid, tacrolimus, cyclophosphamide, ciclosporin or azathioprine)† 630 (32.8%)
 Biologic/Targeted synthetic monotherapy 45 (2.3%)
 Biologic/Targeted and immunosuppressive drug combination therapy† 177 (9.2%)

*All glucocorticoids were converted to prednisone-equivalent doses.

†These patients could be also on antimalarials.

ESRD, end-stage renal disease; SLE, systemic lupus erythematosus.