Skip to main content
. 2022 Feb 14;9:821777. doi: 10.3389/fmed.2022.821777

Table 1.

Major genera in the gut samples of patients with COVID-19 and healthy controls in response to various clinical conditions.

Loss of taste (LoT)
Bacteria Healthy COVID–LoT COVID + LoT p-Value
Streptococcus 1.9 ± 0.4b 3.4 ± 0.4ab 3.5 ± 0.3a 0.01446
Escherichia-Shigella 2.6 ± 0.4b 7.1 ± 0.6a 5.6 ± 0.6a 0.00048
Prevotella 8.9 ± 0.1a 4.4 ± 1.0b 5.3 ± 0.6b 1.8e-05
Enterococcus 1.2 ± 0.6b 4.3 ± 0.9a 5.1 ± 0.7a 0.0003
Bacteroides 2.7 ± 0.6b 5.5 ± 1.3ab 5.6 ± 0.7a 0.0152
Bifidobacterium 2.9 ± 0.4b 5.1 ± 1.0ab 4.7 ± 0.5a 0.0138
Loss of motion (LoM)
Bacteria Healthy COVID–LoM COVID + LoM p -Value
Streptococcus 1.9 ± 0.4b 3.7 ± 0.4a 3.3 ± 0.3a 0.01196
Escherichia-Shigella 2.6 ± 0.4b 6.3 ± 1.0a 5.8 ± 0.6a 0.00094
Prevotella 8.9 ± 0.1a 4.1 ± 0.9b 5.6 ± 0.6b 1.2e-05
Enterococcus 1.2 ± 0.6c 4.2 ± 0.8b 5.2 ± 0.8a 0.00027
Bacteroides 2.7 ± 0.6b 5.1 ± 1.2ab 5.8 ± 0.7a 0.01394
Bifidobacterium 2.9 ± 0.4b 5.0 ± 0.8a 4.8 ± 0.5a 0.01388
Diarrhoea (DRR)
Bacteria Healthy COVID–DRR COVID + DRR p -Value
Streptococcus 1.9 ± 0.4b 3.4 ± 0.3a 3.4 ± 0.4ab 0.01394
Escherichia-Shigella 2.6 ± 0.4c 4.8 ± 0.5b 8.1 ± 0.2a 1.3e-05
Prevotella 8.9 ± 0.1a 4.9 ± 0.6b 5.5 ± 0.9b 2.4e-05
Enterococcus 1.2 ± 0.6c 5.1 ± 0.8a 4.5 ± 0.9b 0.00038
Bacteroides 2.7 ± 0.6b 5.5 ± 0.9ab 5.6 ± 0.7a 0.01498
Bifidobacterium 2.9 ± 0.4b 5.1 ± 0.6a 4.4 ± 0.5ab 0.01125
Medication (MC)
Bacteria Healthy COVID–MC COVID + MC p -Value
Streptococcus 1.9 ± 0.4b 3.3 ± 0.4ab 3.5 ± 0.3a 0.012
Escherichia-Shigella 2.6 ± 0.4b 5.8 ± 0.8a 6.2 ± 0.6a 0.00095
Prevotella 8.9 ± 0.1a 6.2 ± 0.6b 4.0 ± 0.7c 7.3e-06
Enterococcus 1.2 ± 0.6b 4.9 ± 0.9a 4.9 ± 0.7a 0.00041
Bacteroides 2.7 ± 0.6b 5.3 ± 0.8ab 5.8 ± 0.9a 0.01388
Bifidobacterium 2.9 ± 0.4b 4.6 ± 0.6ab 5.1 ± 0.6a 0.01042

Genera with at least 1% read abundance in any of the tested groups were considered for the differential abundance analysis. Relative abundance is shown as mean ± SD. Different superscripts (a, b, c, ab) placed with mean values in the same column convey their significant difference in bacterial abundance with each other.

p-value adjusted with Bonferroni correction.