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. 2022 Feb 14;13:814942. doi: 10.3389/fphar.2022.814942

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Copyright © 2022 Ma, Zheng, Su, Zhang, Liu, Li, Zhang, Gong and Kou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volcano plot and heatmap of the differential endogenous metabolites between the model and EDA group in serum and urine. (A–D) Volcano plot of model and EDA group. (E) Heatmap of the differential endogenous metabolites between the model and EDA group in serum. (F) Heatmap of the differential endogenous metabolites between the model and EDA group in urine. Red represented the metabolites in high abundance; green represented the metabolites in low abundance.