Skip to main content
. 2022 Jan 8;11(1):162–168. doi: 10.1093/toxres/tfab127

Figure 2.

Figure 2

Silica exposure increased inflammasome sensor protein expression. (A) Lung tissue homogenates from the control and silica exposed rats (n=5/group) were subjected to Western Blot analysis for AIM2. β-Actin was used as loading control. Quantitation was analyzed densitometrically using ImageQuant 5.2 software (GE Healthcare, Pittsburgh, PA). **p<0.01. (B–G) Immunochemical staining of AIM2 (B–D) and NLRP3 (E–G) was performed using the lung sections of silica exposed rats (C & F for silica 1-day, D & G for silica 3-days) and control animals (B and E). Solid arrows indicated macrophages, and open arrows indicated lung epithelial cells. Scale bars: 50 μm.