Table 2.

Selective pressure analysis for the site model.

Receptor	Model	np	Ln L	Estimates of parameters				Model compared	LRT P-value	Positive sitesa
TLR5	M2a	14	-2969.998729	p:	0.62742	0.36347	0.00911	M1a vs. M2a	1	No significant sites found
				ω:	0.10344	1.00000	4.70001
	M1a	12	-2970.783667	p:	0.63311	0.36689				Not Allowed
				ω:	0.10281	1.00000
	M8	14	-2969.998943	p0=0.94815	p=0.38730	q=0.78363		M7 vs.M8	0.296470369
				(p1= 0.05185)	ω= 1.98531
	M7	12	-2971.214751	p=0.27144		q=0.44370				Not Allowed
TLR8	M2a	14	-5382.496766	p:	0.29522	0.65107	0.05371	M1a vs. M2a	0.000000000	No significant sites found
				ω:	0.00000	1.00000	13.82641
	M1a	12	-5417.313267	p:	0.42715	0.57285				Not Allowed
				ω:	0.00000	1.00000
	M8	14	-5388.003906	p0=0.74956	p=0.00500	q=1.72148		M7 vs.M8	0.000000000	25 G 0.999**,27 K 0.987*,28 E 0.988*,48 W 1.000**,63 Q 0.988*,92 S 0.987*,275 V 0.995**,414 S 0.984*,501 K 0.985*,753 H 0.985*,761 K 0.987*
				(p1= 0.25044)	ω= 5.39259
	M7	12	-5418.056161	p=0.02508		q=0.01283				Not Allowed
TLR13	M2a	12	-3257.897218	p:	0.73321	0.00000	0.26679	M1a vs. M2a	0.008925285	No significant sites found
				ω:	0.00000	1.00000	2.89533
	M1a	10	-3262.616085	p:	0.46579	0.53421				Not Allowed
				ω:	0.00000	1.00000
	M8	12	-3257.897218	p0=0.73321	p=0.00500	q=2.09224		M7 vs.M8	0.003965279	210 H 0.963*
				(p1= 0.26679)	ω= 2.89538
	M7	10	-3263.427397	p=0.02050		q=0.00751				Not Allowed
TLR22	M2a	16	-5046.424216	p:	0.61339	0.15062	0.23598	M1a vs. M2a	0.000000000	No significant sites found
				ω:	0.00000	1.00000	5.25653
	M1a	14	-5086.643355	p:	0.48532	0.51468				Not Allowed
				ω:	0.00000	1.00000
	M8	16	-5046.642792	p0=0.69561	p=0.00500	q=1.39574		M7 vs.M8	0.000000000	24 T 0.963*,32 R 0.968*,36 A 0.957*,40 G 0.957*,45 S 0.999**,49 P 0.964*,66 K 0.951*,88 T 0.999**,119 K 0.994**,141 R 0.994**,149 T 0.951*,181 R 0.969*
				(p1= 0.30439)	ω= 4.52587					245 E 0.993**,254 S 0.969*,257 T 0.995**,273 Q 0.981*,300 H 0.992**,302 R 0.983*,328 L 0.996**,347 R 0.994**,368 Y 0.958*,373 Q 0.962*,
										395 E 0.995**,397 Y 0.954*,419 A 0.954*,423 S 0.964*,447 N 0.994**,477 V 0.995**,496 Q 0.957*,498 P 0.962*,501 T 0.998**,503 R 0.957*
										520 S 0.968*,544 N 0.991**,559 N 0.991**,571 S 0.972*,590 R 0.950*,642 E 0.954*,663 P 0.969*,707 T 0.977*,709 S 1.000**,760 T 0.960*,
	M7	14	-5090.346350	p=0.03100		q=0.01510				Not Allowed
TLR23	M2a	12	-4560.594806	p:	0.79957	0.00000	0.20043	M1a vs. M2a	0.000457781	No significant sites found
				ω:	0.17464	1.00000	3.91573
	M1a	10	-4568.283926	p:	0.38807	0.61193				Not Allowed
				ω:	0.00000	1.00000
	M8	12	-4560.595092	p0=0.79997	p=5.98663	q=27.59025		M7 vs.M8	0.000389425	333 T 0.976*, 515 S 0.974*
	M7	10	-4568.445931	p=0.02094		q=0.00655	0.00655			Not Allowed

^aOnly PSS with significant posterior probabilities are indicated. Asterisks indicate posterior probabilities P≥95%(*) and p>99%(**).

LRT Statistics (2ΔL) and p-values for the site models on the Nototheniidae sequences of Tlr5, Tlr8, Tlr13, Tlr22, and Tlr23.

"w" symbol is Omega which is calculated by Codeml. This value indicates the classes of sites analyzed (emphasis on estimated).