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(A) Axial 68Ga-BMS-986192 PET scan at 1 h after injection in PD-L1–positive (yellow arrow) and wild-type (blue arrow) U-698-M xenograft–bearing NSG mouse. (B) Ex vivo FACS analysis of PD-L1 expression on wild-type (red) and PD-L1 transduced (blue) tumor cells. (C) Ex vivo hematoxylin–eosin (HE) and anti-PD-L1 immunohistochemistry (IHC) staining of PD-L1–positive and wild-type xenograft tissues.
