TABLE 2.

Posttreatment Renal and Bone Marrow Toxicity Assessment

		Cycle 1		Cycle 2
Parameter	Baseline	1 mo	2 mo	1 mo	2 mo	6 mo
Creatinine (mg/dL)
Subject 1	1.20	1.1	1.10	1.30	1.10	1.60
Subject 2	1.10	0.86	0.94	0.98	1.13	1.00
Subject 3	1.10	1.14	0.95	1.00	1.07	1.10
Platelet (k/mm3)
Subject 1	396	151	215	191	216	165
Subject 2	187	82	128	86	130	189
Subject 3	253	107	150	111	47	173
Absolute neutrophil count (cells/mm3)
Subject 1	5,050	6,510	4,310	5,630	4,560	4,100
Subject 2	6,510	4,500	3,800	4,100	4,800	5,180
Subject 3	3,230	3,393	1,575	3,281	1,332	3,520