FIGURE 3.

Scoring results of autotomy behavior and gait observation and analysis. (A) Modified Wall’s score for rats. No autotomy (score 0) (A1); loss of half of the second toe (score 1) (A2); loss of the first and the third toes (score 1) or complete loss of the second toe (score 2), score 1 + 2 = 3 totally (A3); loss of the first and second toes (score 2 + 2 = 4) (A4); loss of the first and the second toes, half of the third toe, the total score of 2 + 2 + 1 = 5 (A5); the first, second and third toes are missing, the total score is 2 × 3 = 6 (A6). (B) At all time points except the 5^th day (p > 0.05), the autotomy score between the SNT group and the other 2 experimental groups is statistically significantly different (*p < 0.05, ^@p < 0.05). (C) CatWalk XT recorded real-time walking footprints of each group of experimental animals on the 30^th day after surgery (left), representative footprints of rats (middle), and detected the 3D signal intensity of footprints (right). (D) Quantification of Print area (cm²), Max intensity At (%) and Step cycle (s) in each group (^@p < 0.05, ^@@p < 0.01, **p < 0.01).