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. 2022 Feb 25;13:20406223221079246. doi: 10.1177/20406223221079246

Table 1.

RET pathogenic variants and MTC outcomes.

ATA risk level Exon RET pathogenic variant
Moderate 8 p.Gly533Cys
10 p.Cys609Phe/Gly/Arg/Ser/Tyr, p.Cys611Phe/Gly/Ser/Tyr/Trp, p.Cys618Phe/Arg/Ser
11 p.Cys630Arg/Tyr, p.Asp631Tyr, p.Lys666Glu
13 p.Glu768Asp, p.Leu790Phe
14 p.Val804Leu/Met
15 p.Ser891Ala
16 p.Arg912Pro
High 11 p.Cys634Phe/Gly/Arg/Ser/Trp/Tyr
15 p.Ala883Phe
Highest 16 p.Met918Thr

ATA, American Thyroid Association.