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. 2022 Feb 26;13:20406207221080743. doi: 10.1177/20406207221080743

Table 1.

The ongoing clinical trials combining Ixazomib with other immunotherapy regimens and target therapy regimens in treating MCL.

Trial phase Setting ClinicalTrials.gov identifier Study titles
1/2 Relapsed/refractory MCL NCT03323151 A Study of Ixazomib and Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma
2 BTK inhibitor-resistant MCL NCT04047797 Ixazomib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma
1/2 Post-autologous HSC transplant in MCL NCT02632396 Ixazomib & Rituximab after Stem Cell Transplant in Treating Patients with Mantle Cell Lymphoma in Remission
2 Indolent B-cell NHL NCT02339922 Ixazomib Citrate and Rituximab in Treating Patients with Indolent B-Cell Non-Hodgkin Lymphoma
2 Post-treatment maintenance therapy NCT03616782 Ixazomib Maintenance in Patients with Newly Diagnosed Mantle Cell Lymphoma (MCL)

BTK, Bruton’s tyrosine kinase; MCL, mantle cell lymphoma; NHL, non-Hodgkin lymphoma.