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Representative design scheme of bi-layered and multi-layered scaffolds. (A) Polycaprolactone (PCL)/alginate bi-layered scaffold. Reproduced with permission (Yu et al., 2020). Copyright: ©2020 by the authors. (B) A multi-layered scaffold with bone layer (PCaP) connects with chondral layer (PCL) by the melt electrowriting mesh. Reproduced with permission (Diloksumpan et al., 2020). Copyright: ©2020 by the authors.
