Table 1.

Mutation profile of right lung tumor in the patient before treatment with crizotinib.

Gene	Transcript	Exon	Nucleotide change	Alteration	Mutant allele frequency
ARL1-MET fusion	ARL1:NM_001177	1	ARL1 (Exon1)-MET (Exon14)		74.27%
	MET : NM_000245	15
TP53	NM_000546	8	c.811G>T	p.Glu271*	42.39%
AKT1	NM_001014432	6	c.428A>C	p.His143Pro	45.37%
CCND1	NM_053056	1	c.94C>G	p.Leu32Val	49.08%

* a nonsense mutation in a sequence of DNA that results in a premature stop codon.