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. 2022 Feb 14;9:845179. doi: 10.3389/fmolb.2022.845179

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Copyright © 2022 Zheng, Long, Chen, Ji, Shu, Yue, Liao, Ma, Qiao, Liu and Liao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of the antibacterial activity and toxicity of the RIF@Cy5.5-HA-NG. (A) Fluorescence imaging of mice at 0, 6, 12, and 24 h after injection. (B) Fluorescence imaging of major organs (liver, spleen, lung, and kidney) collected from animals at 0, 6, 12, and 24 h after injection. (C) Tissue damage analysis of different important organs in mice after intravenous injection of RIF@HA-NG at different times.