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. 2022 Feb 22;11(2):30. doi: 10.1167/tvst.11.2.30

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Figure 1. — The entire circumference of the TM was injured with a laser, which resulted in an increased IOP. HL3501 showed IOP-lowering effects in the laser-induced OHT rabbit model. (A) The IOP of NZW rabbits over 3 weeks of treatment with vehicle, HL3501 (0.02%), latanoprost (0.005%), or timolol (0.5%). (B) The IOP of NZW rabbits on days 7, 14, and 21. All data are expressed as mean ± SD (n = 4 rabbits per drug-treated group; n = 2 rabbits per vehicle-treated group). #P < 0.05; ##P < 0.01; ###P < 0.001; ####P < 0.0001 versus vehicle by one-way ANOVA with post hoc Dunnett's test.