Table 3.

Rabbit IOP Levels for Each Treatment in the Laser-Induced OHT Rabbit Model

	Mean ± SD
					Change Value (mmHg) vs.
Rabbit IOP (mmHg)	Day 0	Day 7	Day 14	Day 21	Vehicle on Day 21
Vehicle	37.0 ± 1.4	35.5 ± 1.4	34.0 ± 1.4	32.5 ± 0.7	—
HL3501	36.5 ± 1.3	32.5 ± 0.6*	28.0 ± 1.5**	22.8 ± 1.5***	9.7↓
Latanoprost	36.8 ± 1.0	34.3 ± 1.0	31.0 ± 0.8*	26.2 ± 1.3**	6.3↓
Timolol	36.5 ± 1.3	34.8 ± 0.5	32.0 ± 1.2	26.5 ± 0.6**	6.0↓

*P < 0.01, **P < 0.001, ***P < 0.0001 versus vehicle by one-way ANOVA with post hoc Dunnett's test.