(A) Kaplan-Meier overall survival curve by treatment modality: no treatment versus androgen deprivation therapy (ADT) alone, p = 0.47; no treatment or ADT alone versus radiation therapy (RT) alone, RT + ADT, or surgery, p < 0.0001 for all; RT alone versus RT + ADT, p = 0.045; RT versus surgery, p = 0.93; and RT + ADT versus surgery, p = 0.38. (B) Kaplan-Meier overall survival curve by treatment modality for all patients with Charlson-Deyo comorbidity score of 0: no treatment versus ADT alone, p = 0.75; no treatment or ADT alone versus RT alone, RT + ADT, or surgery, p < 0.0001 for all; RT alone versus RT + ADT, p = 0.07; RT versus surgery, p = 0.27; and RT + ADT versus surgery, p = 0.73. ADT = androgen deprivation therapy; RT = radiation therapy.