Table 1.

Summary of data for studies with men undergoing transperineal prostate biopsy without prophylactic antibiotics

Study name (year)	Country	Sample size (n)	Type of study	Age (yr)	Mean or median number of biopsy cores (n)	Anesthesia	Sepsis (n)	Nonseptic infections (n)	All infections (n)
Meyer et al (2018) [66]	USA	43	Retrospective cohort	Median 62 (range 44–73)	12.6	Local only	0	0	0
Ristau et al (2018) [87]a	USA	400	Retrospective cohort	Median 68 (IQR 61–74)	16	Local and sedation	0	0	0
Gorin et al (2020) [11]	USA	94	Prospective cohort	Median 68.8 (range 52–86.4)	12	Local only or sedation only	0	0	0
Wetterauer et al (2020) [113]a	Switzerland	177	Retrospective cohort	Median 66 (range 49–86)	13	Local only	0	0	0
Szabo (2021) [100]a	USA	212	Retrospective cohort	Median 63 (range 29–93)	20	Local only	0	0	0
John et al (2021) [13]a	UK	164	Prospective cohort	Median 71 (IQR 67–75)	23	Local only	0	0	0
Lopez et al (2021) [14]a	UK, New Zealand, Hong Kong	175	Prospective cohort	Median 68 (IQR 62–72)	24	Local only	0	0	0
Miller et al (2005) [69]	Australia	81	Retrospective cohort	Mean 69.5 (95% CI 68.1–70.9)	18	Local only	1	0	1
Dimmen et al (2012) [10]	Norway	69	Retrospective cohort	Median 64.5 (range 50–78)	18.4	Local and sedation	1	1	2
Jacewicz et al (2020) [12]a	Multinational	230	Retrospective cohort	Mean 67 (95% CI 66–68)	NR	Local only	1	1	2
Sigle et al (2021) [91]	Germany	184	Retrospective cohort	Median 66.9 (IQR 61.8–72.0)	41	General	0	2	2
Gunzel et al (2021) [17]	Germany	621	Retrospective cohort	Median 68 (IQR 62–74)	10	Local only	1	3	4
Huang et al (2019) [46]	Taiwan	130	RCT	Mean 66.6 (SD 8.81)	10	General or local only	0	6	6
Ding et al (2021) [34]	China	2192	Retrospective cohort	Mean 67.63 (SD 7.11)	22	NR	0	41	41

CI = confidence interval; IQR = interquartile range; NR = not recorded; RCT = randomized controlled trial; SD = standard deviation.

^aStudies with cohorts of men undergoing transperineal prostate biopsy with and without prophylactic antibiotics.