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. 2022 Feb 14;9:811269. doi: 10.3389/fmolb.2022.811269

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Copyright © 2022 Liu, Huang, Chen, Zhang, Li, Wu, Xiong and Jie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clinicopathological features in the high- and low-risk score group, TME analysis. (A) Heat map of clinicopathological features in the high- and low-risk group. (B) Waterfall plot displays mutation information of the genes with high mutation frequencies in the high-risk group. (C) Waterfall plot displays mutation information of the genes with high mutation frequencies in the low-risk group. (D) TMB difference in the high- and low-risk patients. (E) Kaplan–Meier curve analysis of OS is shown for patients in high and low TMB. (F) Kaplan–Meier curve analysis of OS is shown for patients classified according to the TMB and necroptosis-related lncRNA model.