Table 2.

Investigator-assessed confirmed best overall response by Response Evaluation Criteria In Solid Tumors V.1.1

	All phase I SA patients (N=134) n (%)	All phase I combo patients (N=121) n (%)
Best overall response
Complete response (CR)	0	3 (2.5)
Partial response (PR)	0	10 (8.3)
Stable disease (SD)	32 (23.9)	35 (28.9)
Progressive disease (PD)	82 (61.2)	55 (45.5)
Non-CR/non-PD (NCRNPD)	2 (1.5)	1 (0.8)
Unknown	18 (13.4)	17 (14.0)
Overall response rate (CR+PR) 90% CI	0 (0.0 to 2.2)	13 (10.7) (6.5 to 16.5)
Disease control rate (CR+PR+SD) 90% CI	34 (25.4) (19.3 to 32.3)	49 (40.5) (33.0 to 48.4)

CI, confidence interval; SA, single-agent.