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. 2022 Feb 24;35(1):e100724. doi: 10.1136/gpsych-2021-100724

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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A simplified schematic of the reward circuit in the human brain. ACC, anterior cingulate cortex; Amy, amygdala; DS, dorsal striatum; LHb, lateral habenula; mPFC, medial prefrontal cortex; MSNs, medium spiny neurons; NAc, nucleus accumbens; OFC, orbitofrontal cortex; RMTg, rostromedial tegmental nucleus; SN, substantia nigra; VTA, ventral tegmental area.