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. 2022 Feb 14;10:809425. doi: 10.3389/fcell.2022.809425

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Copyright © 2022 Guo, Tai, Wang, Sun, Zhang, Wei, Xiang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The interaction site of the Gα_12/13 isoform. (A) The interaction sites on the amino acid fragment of Gα₁₂ isoforms. (B) The interaction sites on the amino acid fragment of Gα₁₃ isoforms. The information on the interaction sites of Gα₁₂ and Gα₁₃ is from NCBI. In NCBI reference sequence database, the human GNA12 isoforms are NP_031379.2, NP_001269369.1, NP_001269370.1, and NP_001280021.1. (https://www.ncbi.nlm.nih.gov/gene/2768). The human GNA13 isoforms are NP_006563.2 and NP_001269354.1. (https://www.ncbi.nlm.nih.gov/gene/10672).