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. 2021 Nov 29;186(1):83–101. doi: 10.1093/toxsci/kfab143

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© The Author(s) 2021. Published by Oxford University Press on behalf of the Society of Toxicology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 8. — Reduced representation bisulfite sequencing of the DNA from liver samples from female Sprague-Dawley rats exposed to glyphosate or its formulated product Roundup MON 52276. A, Distribution of percentage methylation per base B, CpG methylation around TSS. (C) Circos plot shows the location of differentially methylated CpG sites (blue track, hypomethylated; red track, hypermethylated; round symbols in outer tracks, glyphosate; cross symbols in inner tracks, MON 52276). D, Correlation of methylation changes for MON 52276 and glyphosate (n = 12 per group).