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(A) Experimental and adjusted concentration-time profiles of paromomycin after oral administration of an immediate-release tablet of 250 mg of paromomycin during a phase I contractile activity. (B) Experimental and simulated concentration-time profiles of paromomycin after oral administration of an immediate-release tablet of 250 mg of paromomycin during a phase II contractile activity. All observed data were obtained from literature [11].
