Table 5.
Applied values to simulate the average gastric and duodenal concentrations of paromomycin as a function of time in fasted state conditions after oral administration.
| Mean profile | |
|---|---|
| t1/2 (min) antrum | 2.71 |
| t1/2 (min) body | 22.1 |
| t1/2 (min) bypass | 6 |
| t1/2 (min) duodenum | 0.76 |
| Fraction bypassed | 0.49 |