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. 2022 Feb 23;17:395–404. doi: 10.2147/COPD.S347607

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© 2022 Zhang et al.

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Serum C1q levels were downregulated in 44 follow-up severe exacerbators (A). Diagnostic accuracy of serum C1q to differentiate severe exacerbations in 144 follow-up COPD subjects (B). Area under the curves (AUC) was 0.762, and the cutoff value was set to 137.150 mg/L. Differences between subjects with low and high C1q levels in time to the next severe exacerbation (C) and time to death (D). ***P < 0.001.