5. Results of subgroup analyses (survival ‐ combination CT trials only).
Subgroup | Categories | Interaction | Trend |
Age | ≺55, 55 to ≺ 65, ≧ 65 | 1.572 (2 d.f.) P=0.456 | 0.482 (1 d.f.) P=0.488 |
Sex | Male, Female | 0.266 (1d.f) P=0.606 | ‐ |
T category | T1‐2, T3, T4 | 0.324 (2 d.f.) P=0.850 | 0.108 (1 d.f.) P=0.742 |
N category | N0, N1/N2 | 0.080 (1d.f.) P=0.777 | ‐ |
Grade | G1/G2, G3/G4 | 1.154 (1d.f.) P=0.283 | ‐ |
Tumour diameter (cm) | ≺ 2.5, 2.5 to 5.0, ≻ 5.0 | 7.733 (2 d.f.) P=0.021 | 7.079 (1d.f.) P=0.008 |
Performance status | 0, 1, 2 to 3 | 1.511 (2 d.f.) P=0.470 | 0.004 (1 d.f.) P=0.95 |
Renal function (GFR) | ≦ 59, 60 to 69, ≻ 69 | 3.573 (2 d.f.) P=0.168 | 3.564 (1d.f.) P=0.059 |
d.f. = degrees of freedom |