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. 2004 Jan 26;2004(1):CD005246. doi: 10.1002/14651858.CD005246

Wallace 1991.

Methods RCT 
 Accrual 1984‐1988
Participants 159 
 T2‐T4, Nx, M0
Interventions Radiotherapy alone vs. Neoadjuvant chemotherapy + radiotherapy
Neoadjuvant CT: 
 3 cycles every3 weeks of Cisplatin (100mg/m2)
Outcomes Survival
Notes Single‐agent cisplatin
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Low risk A ‐ Adequate