Figure 4.

Subtype-specific clusters of co-occurring genetic alterations. The frequency (bar graph) and over- or under-representation (blue to red scale) of mutations and structural alterations is shown on the left for Burkitt lymphoma, diffuse large B-cell lymphoma, follicular lymphoma and mantle cell lymphoma. The correlation matrix of co-associated (green) and mutually exclusive (purple) relationships was clustered to identify seven groups of co-occurring genetic alterations that were predominantly over-represented in a single subtype of B-cell non-Hodgkin lymphoma. BL: Burkitt lymphoma; DLBCL: diffuse large B-cell lymphoma; FL: follicular lymphoma; MCL: mantle cell lymphoma