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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Virology. 2021 Apr 6;559:111–119. doi: 10.1016/j.virol.2021.03.008

Figure 5. 2-DG and DCA treatment significantly alter BALF cytokine and chemokine responses to IAV infection.

Figure 5.

Effect of mock and IAV infection (FLU) and treatment with 2-DG, DCA, or ROT on day 6 BALF levels of: (A) IFN-γ (ng/ml); (B) IL-6 (ng/ml); (C) IL-10 (pg/ml); and (D) KC/CXCL-1 (ng/ml). All n = 5/group (from 2 independent mock or IAV infections per group). Data in box represent first quartile, median, and third quartile for each experimental group. Whiskers indicate highest and lowest sample values within the group. N.D.: none detected. *: P<0.05, **: P<0.005, #: P<0.001, vs. IAV-infected mice. ‡: P<0.005, §: P<0.001, vs. 2-DG-treated, IAV-infected mice.