Table 2: Differentiation transcript analysis.

Values are reported as mean ± SD. Statistics were generated using a one-way ANOVA with Tukey’s test for multiple comparisons.

Pathway	Gene	Cocktail	DMSO	SCO	ROSI
Early Differentiation	Cebpb	Vehicle	0.47 ± 0.04	0.60 ± 0.10 *p=0.01; $p=0.004	0.46 ± 0.04
		MDI	1.99 ± 0.37	2.21 ± 0.37	2.25 ± 0.56
		DI	0.83 ± 0.14	1.09 ± 0.37	0.83 ± 0.24
		D	0.78 ± 0.20	1.11 ± 0.23 *p=0.01; $p=0.04	0.84± 0.14
	Cebpd	Vehicle	0.24 ± 0.12	0.17 ± 0.07	0.19 ±0.07
		MDI	0.45 ± 0.13	0.63 ± 0.41	0.39 ± 0.14
		DI	1.25 ± 0.47	1.41 ± 0.29	1.14 ± 0.21
		D	1.73 ± 0.55	1.71 ± 0.47	1.30 ± 0.19
	Klf5	Vehicle	0.20 ± 0.14	0.28 ± 0.16	0.37 ± 0.26
		MDI	1.24 ± 0.53	1.43 ± 0.75	1.74 ± 0.79
		DI	0.75 ± 0.29	0.97 ± 0.47	1.06± 0.46
		D	0.84 ± 0.47	0.96 ± 0.39	1.04 ± 0.42
Late Differentiation	Pparg	Vehicle	0.19 ± 0.05	0.23 ± 0.02	0.26 ± 0.03
		MDI	1.87 ± 0.51	3.79 ± 0.36 *p=0.005	3.09 ± 0.25 *p=0.03
		DI	0.37 ± 0.08	0.93 ± 0.13 *p=0.002	1.89 ± 0.13 *p<0.0001; $p=0.0001
		D	0.32 ± 0.08	0.39 ± 0.07	0.61 ± 0.15 *p=0.035
	Cebpa	Vehicle	0.07 ± 0.01	0.12 ± 0.02	0.23 ± 0.06 *p=0.004; $p=0.021
		MDI	1.02 ± 0.62	2.91 ± 0.48 NS, p=0.089	4.16 ± 0.99 *p=0.013
		DI	0.06 ± 0.02	0.57 ± 0.16	3.19 ± 0.75 *p=0.003; $p=0.0009
		D	0.05 ± 0.01	0.10 ± 0.01	0.65 ± 0.07 *$p<0.0001
	Stat5a	Vehicle	0.36 ± 0.09	0.43 ± 0.03	0.59 ± 0.13 *p=0.041
		MDI	1.05 ± 0.05	1.64 ± 0.20 *p=0.041	2.72 ± 0.21 *p=0.0004; $p=0.002
		DI	0.53 ± 0.04	0.87 ± 0.09 *p=0.005	1.19 ± 0.09 *p=0.0001; $p=0.007
		D	0.54 ± 0.12	0.60 ± 0.04	0.93 ± 0.06 *p=0.003; $p=0.006

^*indicates significance compared to DMSO and $ indicates significance when comparing SCO and ROSI.