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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Obesity (Silver Spring). 2021 Jul 5;29(8):1309–1319. doi: 10.1002/oby.23199

Table 3: Lipid accumulation transcript analysis.

Values are reported as mean ± SD. Statistics were generated using a one-way ANOVA with Tukey’s test for multiple comparisons.

Gene Cocktail DMSO SCO ROSI
Cd36 Vehicle 0.0002±0.0003 0.02±0.007 0.36±0.24
p=0.013; $p=0.017
MDI 0.56 ±0.12 2.69 ± 0.24
*p<0.0001
5.71 ± 0.50
*$p<0.0001
DI 0.01 ± 0.004 0.88 ± 0.18 4.61 ± 2.53
*p=0.004; $p=0.014
D 0.002 ± 0.0002 0.11 ± 0.02 1.33 ± 0.80
*p=0.007; $p=0.012
Srebf1 Vehicle 0.35 ± 0.03 0.48 ± 0.03 0.62 ± 0.15
*p=0.005
MDI 1.30 ± 0.16 2.18 ± 0.21
*p=0.001
2.54 ± 0.29
*p<0.0001
DI 0.60 ± 0.12 1.12 ± 0.13
*p=0.005
2.05 ± 0.23
*$p<0.0001
D 0.65 ± 0.13 D 0.96 ± 0.24 1.57 ± 0.07
*p<0.0001; $p=0.001
Fabp4 Vehicle 0.0001 ± 0.00003 0.004 ± 0.001 4.35 ± 0.15
*$p<0.0001
MDI 0.20 ± 0.08 1.81 ± 0.40
*p=0.035
3.78 ± 1.23
*p=0.0002; $p=0.012
DI 0.02 ± 0.005 0.47 ± 0.18
*p=0.016
0.84 ± 0.25
*p=0.0003; $p=0.037
D 0.02 ± 0.003 0.09 ± 0.003 0.54 ± 0.60
Lpl Vehicle 0.24 ± 0.03 0.40 ± 0.03 5.30 ± 1.49
*$p<0.0001
MDI 1.36 ± 0.42 3.96 ± 0.42
*p<0.0001
4.71 ± 0.58
*p<0.0001
DI 0.24 ± 0.04 1.06 ± 0.18
*p<0.0001
1.30 ± 0.13
*p<0.0001
D 0.24 ± 0.03 0.40 ± 0.01 0.98 ± 0.51
*p=0.014; $p=0.048
Fasn Vehicle 0.12 ± 0.01 0.16 ± 0.02
*p=0.008
0.19 ± 0.01
*p=0.0002; $p=0.043
MDI 1.25 ± 0.42 4.34 ± 0.88
*p=0.003
4.60 ± 1.25
*p=0.002
DI 0.22 ± 0.01 0.56 ± 0.01
*p<0.0001
2.23 ± 0.11
*$p<0.0001
D 0.25 ± 0.05 0.30 ± 0.01 0.72 ± 0.15
*p=0.0001; $p=0.0003
Glut4 Vehicle 0.002 ± 0.002 0.01 ± 0.01 16.35 ± 0.62
*$p<0.0001
MDI 0.36 ± 0.26 6.06 ± 3.23
*p=0.016
6.53 ± 2.25
*p=0.01
DI 0.01 ± 0.01 0.51 ± 0.23
*p=0.004
0.75 ±0.13
*p=0.0002
D 0.01 ± 0.01 0.04 ± 0.01 0.37 ± 0.44
*

indicates significance compared to DMSO and $ indicates significance when comparing SCO and ROSI.