Baseline predictors of longitudinal tau accumulation. Pearson correlations between FTP slope, indicating the rate of longitudinal tau accumulation, and baseline risk factors. A, Higher age at baseline significantly predicted increased FTP slope in entorhinal cortex (EC). B, Higher baseline EC FTP was associated with increased FTP slope in EC and parahippocampal cortex (PHC), but not in inferior temporal gyrus (IT). C, Higher baseline global PiB was associated with increased FTP slope in EC, PHC, and IT. ***p < 0.001, **p < 0.01, *p < 0.05, +p < 0.10.