Table 3.
Controls (I) | Pre-Therapy DLBCL (II) | Post-Therapy DLBCL (III) | p | ||||
---|---|---|---|---|---|---|---|
N = 19 | N = 20 | N = 20 | I vs. II | I vs. III | II vs. III | ||
CD20+ % | Median | 24 | 22 | 10 | 0.525 | <0.001 * | <0.001 ** |
IQR | (20–25) | (18.3–26.8) | (9.6–11.8) | ||||
PDL-1+CD20+ % | Median | 1 | 16 | 6.8 | <0.001 ** | <0.001 * | <0.001 ** |
IQR | (0.8–1) | (15–23) | (6–7.9) | ||||
PD-1+CD20+ % | Median | 0.7 | 9 | 0.9 | <0.001 ** | 0.575 | <0.001 ** |
IQR | (0.6–1) | (8–11) | (0.6–1) |
Group I: Healthy volunteers; Group II: Pre-therapy DLBCL patients; Group III: Patients completed 6 CHOP cycles. N: Number; IQR: Interquartile range. Kruskal Wallis test was used for the analysis of data between the three groups followed by pairwise comparisons between every two groups using Bonferroni correction. Significant differences are identified with asterisks (*). High significant differences are identified by an asterisk (**) (p < 0.001).