54. Effect size based on Standardised Mean Difference ‐ Part III.

Product	Comparison	Outcome	1‐4 wk	5‐13 wk	14‐26 wk	45‐52 wk
NASHA (Durolane)	Saline	WOMAC pain (Likert: 0‐20)
		WOMAC stiffness (Likert: 0‐8)
		WOMAC physical function (Likert: 0‐68)
		Patient global assessment (Likert: 1‐5)
		SF‐36 physical componet summary ( )
		SF‐36 mental component summary ( )
NRD‐101 (Suvenyl)	Placebo	Pain (0‐100 mm VAS)
		Lequesne Index (0‐24)
		Patient global assessment (0‐100 mm VAS)
		Percentage of painful days during the previous month (0‐100 mm VAS)
NRD‐101 (Suvenyl)	Diacerein	Pain (0‐100 mm VAS)
		Lequesne Index (0‐24)
		Patient global assessment (0‐100 mm VAS)
		Percentage of painful days during the previous month (0‐100 mm VAS)
Hyalgan+exercise+ultrasound	Exercise+ultrasound	Pain (0‐10 cm VAS)
		Lequesne Index (0‐26)
		Range of motion (degrees)
		Ambulation speed (metres/minute)
		Mean peak torque at 60 degrees per second (flexion/concentric)
		Mean peak torque at 180 degrees per second (flexion/concentric)
Hyalgan+exercise+ultrasound	Exercise	Pain (0‐10 cm VAS)
		Lequesne Index (0‐26)
		Range of motion (degrees)
		Ambulation speed (metres/minute)
		Mean peak torque at 60 degrees per second (flexion/concentric)
		Mean peak torque at 180 degrees per second (flexion/concentric)
Hyalgan+exercise+ultrasound	Control warmup exercises	Pain (0‐10 cm)
		Lequesne Index (0‐26)
		Range of motion (degrees)
		Ambulation speed (metres/minute)
		Mean peak torque at 60 degrees per second (flexion/concentric)
		Mean peak torque at 180 degrees per second (flexion/concentric)
Hylan G‐F 20	Exercise programme	Hospital for Special Surgery Knee Score