Comparison 14. (Hyalgan plus exercise plus ultrasound) versus control warmup exercise.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pain (0‐10 cm VAS)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
1.1 End of treatment	1	66	Mean Difference (IV, Fixed, 95% CI)	‐2.40 [‐3.08, ‐1.72]
1.2 One‐year follow‐up	1	60	Mean Difference (IV, Fixed, 95% CI)	‐4.6 [‐5.32, ‐3.88]
2 Lequesne Index (0‐26)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
2.1 End of treatment	1	66	Mean Difference (IV, Fixed, 95% CI)	‐2.90 [‐3.41, ‐2.39]
2.2 One‐year follow‐up	1	60	Mean Difference (IV, Fixed, 95% CI)	‐5.60 [‐6.38, ‐4.82]
3 Range of motion (degrees)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
3.1 End of treatment	1	66	Mean Difference (IV, Fixed, 95% CI)	22.0 [16.42, 27.58]
3.2 One‐year follow‐up	1	60	Mean Difference (IV, Fixed, 95% CI)	26.0 [17.14, 34.86]
4 Ambulation speed (metres per minute)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
4.1 End of treatment	1	66	Mean Difference (IV, Fixed, 95% CI)	19.80 [18.17, 21.43]
4.2 One‐year follow‐up	1	60	Mean Difference (IV, Fixed, 95% CI)	29.20 [26.18, 32.22]
5 Safety: total withdrawals overall	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
5.1 During treatment	1	70	Risk Ratio (M‐H, Fixed, 95% CI)	0.33 [0.04, 3.05]
5.2 Overall	1	70	Risk Ratio (M‐H, Fixed, 95% CI)	0.43 [0.12, 1.52]