1 Spontaneous pain (0‐100 mm VAS) |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
1.1 1 to 4 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
20.5 [10.21, 30.79] |
1.2 5 to 13 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐4.0 [‐14.48, 6.48] |
1.3 14 to 26 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
2.20 [‐8.23, 12.63] |
1.4 37 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
1.0 [‐9.15, 11.15] |
1.5 45 to 52 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐10.5 [‐21.47, 0.47] |
2 WOMAC pain |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
2.1 1 to 4 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐3.0 [‐4.85, ‐1.15] |
2.2 5 to 13 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐3.10 [‐5.12, ‐1.08] |
2.3 14 to 26 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.90 [‐3.33, 1.53] |
2.4 37 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐1.90 [‐3.71, ‐0.09] |
2.5 45 to 52 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐5.30 [‐7.50, ‐3.10] |
3 WOMAC physical function |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
3.1 1 to 4 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
2.5 [‐6.35, 11.35] |
3.2 5 to 13 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
2.80 [‐5.75, 11.35] |
3.3 14 to 26 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [‐9.30, 9.30] |
3.4 37 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
0.40 [‐6.88, 7.68] |
3.5 45 to 52 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
0.70 [‐6.84, 8.24] |
4 SF‐36 pain |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
4.1 1 to 4 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
0.30 [‐11.18, 11.78] |
4.2 5 to 13 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
2.60 [‐9.69, 14.89] |
4.3 14 to 26 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
1.10 [‐13.22, 15.42] |
4.4 37 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐7.5 [‐17.09, 2.09] |
4.5 45 to 52 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐3.5 [‐15.18, 8.18] |
5 SF‐36 physical functioning |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
5.1 1 to 4 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
3.5 [‐12.00, 19.00] |
5.2 5 to 13 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
8.20 [‐4.48, 20.88] |
5.3 14 to 26 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
1.70 [‐13.64, 17.04] |
5.4 37 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐4.20 [‐17.28, 8.88] |
5.5 45 to 52 weeks post‐injection |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
1.0 [‐14.09, 16.09] |